User:Gary An

Current Position:

Trauma/Burn Surgeon

Cook County Hospital

Chicago, IL

Contact Information

201 East Huron, Galter 10-105

Chicago, IL 60611

Phone: 312-695-4838

Fax: 312-695-1462

Email: docgca@aol.com

Current Research

Utilization of Agent Based Modeling to characterize acute inflammation at a cellular and molecular level. Focus is primarily on the pathophysiology of sepsis and multiple organ failure. Currently using primarily StarlogoT and Netlogo.

Complexity/Modeling Publications

An G. Concepts for developing a collaborative in-silico model of the acute inflammatory response using agent based modeling. J Crit Care 2006; 21(1): 105-110.

An G. Phenomenological issues related to measurement, mechanisms and manipulation of complex biological systems. Crit Care Med 2006; 34(1): 245-246. (Editorial)

An G. Introduction of an in-sIlico syntactical grammar for translating basic science research into agent based models of the acute inflammatory response. Proc 11th Congress Eur Shock Soc 2005, H Redl editor. 161-165.

An G. Mathematical modeling in medicine: A means not an end. Crit Care Med 2005; 33(1): 253-254. (Editorial)

Vodovotz Y, Clermont G, Chow C, An G. Mathematical models of the acute inflammatory response. Cur Opin Crit Care 2004; 10:383-390.

An G. In-silico experiments of existing and hypothetical cytokine-directed clinical trials using agent based modeling. Crit Care Med 2004; 32(10): 2050-2060..

An G. Complexity theory and surgery: Introducing and integrating a new analytical paradigm. New Surg 2001; 1(3): 175-179.

An G. Agent-based computer simulation and SIRS: Building a bridge between basic science and clinical trials. Shock 2001; 16(4): 266-273.

An G, Lee I. Agent-Based Computer simulation (ABCS) and the inflammatory response: Building a tool to study Systemic Inflammatory Response Syndrome (SIRS).Simulation and Gaming 2001; 32(3): 344-361.

An G, Lee I. Complexity, Emergence and Pathophysiology: Using Agent Based Computer Simulation to characterize the Non-Adaptive Inflammatory Response. InterJournal Complex Systems: http://www.interjournal.org. Manuscript # [344]. May, 2000.

Links

Link to Society of Complexity in Acute Illness (SCAI). This is an organization of physicians and biomedical researchers committed to promoting the use of mathematical modeling and computational methods to analyze the pathophysiology of acute illnesses with a focus on inflammation. http://www.scai-med.org

Link to the annual meeting of SCAI, called the International Conference on Complexity in Acute Illness (ICCAI). http://www.iccia.org

Link to Modeling Glossary developed and maintained by the Biosystems Research Group at the University of California, San Francisco under the leadership of C. Anthony Hunt. This Glossary can be used as a reference point by those interested in biomedical modeling as a means of fostering communication between modelers and domain specialists. http://biosystems.ucsf.edu/Researc/dictionary.html